PEG MGF
$45.99
2mg
PEG-MGF (Pegylated Mechano Growth Factor) is a modified form of an IGF-1 splice variant designed to extend its duration of activity. It has been studied in research settings for its role in muscle-related signaling pathways, including processes involved in cellular growth, repair, and regeneration mechanisms.
Usage Disclaimer: Research Use Only. This product is intended strictly for laboratory research and in-vitro studies. It is not for human or animal consumption, medical use, or diagnostic purposes. Any unauthorized use of this product is strictly prohibited.
FDA Compliance: FDA Notice. The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Research Studies
MGF Inflammatory Response Study (Doroudian et al., 2018)
Mouse muscle injury model | MGF overexpression | 14 days | Macrophage analysis
MGF overexpression modulated inflammatory cytokine expression and enhanced macrophage resolution during skeletal muscle injury recovery. Suggests MGF plays role in coordinating inflammatory-to-regenerative phase transition.
MGF-E Peptide Human Muscle Cell Study (Kandalla et al., 2011)
Human satellite cells | In vitro | Neonatal, 15yr, 73yr donors | Doses: 3-100ng/ml
Landmark study testing MGF-24aa-E peptide on human satellite cells from different ages. Found significant cell proliferation increase even at 3ng/ml (P<0.001), with 100ng/ml showing largest effect. MGF increased proliferative lifespan and delayed senescence in neonatal and young adult cells, but NOT in old adult (73yr) cells. Hypertrophy with decreased reserve cells observed in ALL age groups. Authors concluded MGF could combat sarcopenia without IGF-1 oncogenic side effects.
Human Myoblast Migration & Transplantation (Mills et al., 2007)
Human cells | In vivo | MGF-24aa-E peptide | Cell transplantation
MGF-24aa-E peptide was shown to favor in vivo migration of human myoblasts and improve human precursor cell transplantation outcomes, suggesting applications for cell-based therapies.
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