MOTS-C (Mitochondrial Peptide)
$34.99
MOTS-c is a 16–amino acid mitochondrial-derived peptide encoded by the mitochondrial genome. It has been studied in research settings for its role in metabolic signaling pathways, cellular stress responses, and regulatory mechanisms related to energy balance and gene expression.
Usage Disclaimer: Research Use Only. This product is intended strictly for laboratory research and in-vitro studies. It is not for human or animal consumption, medical use, or diagnostic purposes. Any unauthorized use of this product is strictly prohibited.
FDA Compliance: FDA Notice. The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Research Studies
Gestational Diabetes Mellitus (2022)
Mice | Daily administration during pregnancy | Throughout pregnancy | Alleviated hyperglycemia, improved maternal-fetal outcomes
Yin et al. showed MOTS-c significantly alleviated hyperglycemia in GDM mouse model, improved insulin sensitivity, and reduced birth weight abnormalities. Human study found significantly lower serum MOTS-c levels in GDM patients versus controls.
Acute Exercise Enhancement (2022)
Mice & Rats | 15 mg/kg single dose i.v. | Acute administration | 12% increased running time, 15% increased distance
Hyatt et al. showed single dose MOTS-c improved running time by 12% and distance by 15% in untrained mice. Chronic training increased MOTS-c protein expression 1.5-5-fold in muscle tissue, demonstrating both acute and chronic exercise-enhancing effects.
Exercise Performance and Age-Dependent Physical Decline (2021)
Mice & Humans | 15 mg/kg 3x weekly (mice) | Variable duration | Enhanced physical performance across all age groups
Reynolds et al. demonstrated MOTS-c significantly enhanced physical performance in young, middle-aged, and old mice. Exercise induced 11.9-fold increase in skeletal muscle MOTS-c in humans. Acts as mitochondrial-encoded regulator of age-dependent physical performance.
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