Glutathione
$72.99
1500mg
Glutathione (GSH) is a naturally occurring tripeptide composed of glutamate, cysteine, and glycine. It is widely studied for its role in cellular redox balance, antioxidant defense systems, and metabolic detoxification pathways, and is present in virtually all cells.
Usage Disclaimer: Research Use Only. This product is intended strictly for laboratory research and in-vitro studies. It is not for human or animal consumption, medical use, or diagnostic purposes. Any unauthorized use of this product is strictly prohibited.
FDA Compliance: FDA Notice. The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Research Studies
High-dose IV Glutathione Pharmacokinetics - Aebi et al.
Human | 2g/m² IV infusion | Rapid clearance | t½ ~14 minutes
Classic pharmacokinetic study demonstrating that IV glutathione significantly increases plasma levels but has a short half-life (~14 minutes), with rapid conversion to cysteine and other metabolites.
Glutathione in Parkinson's Disease - Substantia Nigra Depletion
Human | Post-mortem | 40% reduction in substantia nigra
Landmark study showing GSH levels were reduced by 40% in the substantia nigra of Parkinson's patients compared to controls, establishing the oxidative stress connection in PD pathogenesis.
Intranasal Glutathione Phase IIb Trial - Mischley et al.
Human | 45 PD patients | 3 months | Intranasal GSH
Double-blind, placebo-controlled trial found intranasal glutathione increased brain GSH levels and showed mild motor improvement in Parkinson's patients, though placebo group also improved.
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