Hexarelin Acetate
$27.99
Hexarelin (Examorelin) is a synthetic hexapeptide studied in research settings for its activity as a growth hormone–releasing peptide (GHRP) through the ghrelin receptor (GHS-R1a). It has also been investigated for its interactions with additional receptor pathways and its potential role in endocrine and metabolic signaling mechanisms.
Usage Disclaimer: Research Use Only. This product is intended strictly for laboratory research and in-vitro studies. It is not for human or animal consumption, medical use, or diagnostic purposes. Any unauthorized use of this product is strictly prohibited.
FDA Compliance: FDA Notice. The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Research Studies
Growth Hormone-Releasing Activity of Hexarelin in Humans (1994)
Human | 0.5-2 μg/kg IV | Single dose | 12 adult males
Double-blind, placebo-controlled dose-response study demonstrating dose-dependent GH release. Peak plasma GH at 30 minutes, returning to baseline within 240 minutes. Cmax values: 26.9 ng/ml (0.5 μg/kg), 52.3 ng/ml (1 μg/kg), 55.0 ng/ml (2 μg/kg) vs 3.9 ng/ml placebo.
Hexarelin Treatment Preserves Myocardial Function After MI (2018)
Mouse model | 0.3 mg/kg/day SubQ | 21 days | LAD ligation
Demonstrated significant improvement in LV function after 14 days. Hexarelin treatment reduced LV collagen concentration by ~53%, decreased inflammatory cytokines (TNF-α, IL-1β), and shifted autonomic balance toward parasympathetic predominance.
Protective Effects of Hexarelin in ALS Neuroblastoma Model (2023)
In vitro | 1 μM | Human neuroblastoma cells | SOD1-G93A mutation
Hexarelin protected cells from H2O2-induced cytotoxicity by increasing Bcl-2 expression, reducing caspase-3 activation, and modulating MAPK/Akt pathways. Significantly decreased γH2AX positive cells indicating DNA damage protection.
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